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All Other Cancers - Late-Stage Diagnosis

Late-stage diagnosis is a term used to describe cancer that is far along in its growth and has spread to the lymph nodes or other places in the body. The risk factors are described for other cancer types, outside of the priority cancers previously described, that are most common for late-stage diagnosis.

Bladder Cancer

Risk Factors

  • Family history of bladder cancer
  • Gene mutations
  • Smoking
  • Exposure to chemicals, such as processing paint, dye, metal, and petroleum products
  • Drinking well water contaminated with arsenic
  • Chronic urinary tract infections

Brain Cancer

Risk Factors

  • No one known cause
  • Some brain cancers can be linked to family history, radiation exposure and a weakened immune system
  • Genetic disorders

Esophageal Cancer

Risk Factors

  • Smoking
  • Drinking alcohol
  • Gastroesophageal reflux disease (GERD)
  • HPV

Kidney and Renal Pelvis Cancer

Risk Factors

  • Smoking
  • High blood pressure
  • Taking certain pain medicine for a long period of time
  • Having hepatitis C
  • Having kidney stones
  • Having the sickle cell trait
  • Being exposed to trichloroethylene

Leukemia

Risk Factors

  • No one known cause
  • Smoking
  • Family history of leukemia
  • Previous cancer treatment
  • Exposure to certain chemicals
  • Genetic disorders

Liver Cancer

Risk Factors

  • Hepatitis B or C
  • Smoking
  • Drinking alcohol
  • Having cirrhosis
  • Having nonalcoholic fatty liver disease
  • Diabetes

Non-Hodgkin Lymphoma

Risk Factors

  • Family history
  • Radiation exposure
  • Having a weakened immune system
  • Autoimmune disease
  • Certain infections

Oral Cavity and Pharynx Cancer

Risk Factors

  • Tobacco use
  • Drinking alcohol
  • HPV
  • Ultraviolet (UV) light
  • Weakened immune system

Ovarian Cancer

Risk Factors

  • Middle-aged or older
  • Family history or gene mutations
  • Have had breast, uterine, or colorectal cancer
  • Have a genetic mutation of BRCA1 or BRCA2 or one associated with Lynch syndrome
  • Have endometriosis
  • Have an Eastern European or Ashkenazi Jewish background
  • Never have given birth

Pancreatic Cancer

Risk Factors

  • Smoking
  • Obesity
  • Diabetes
  • Chronic pancreatitis
  • Exposure to certain chemicals

Stomach Cancer

Risk Factors

  • H. pylori infection
  • Smoking
  • Drinking alcohol
  • Previous stomach surgery
  • Being overweight or obese
  • Genetic disorders

Thyroid Cancer

Risk Factors

  • Family history
  • Radiation exposure
  • Iodine in your diet
  • Inherited genetic conditions

Uterine Cancer

Risk Factors

  • Older than 50 years of age
  • Taken estrogen by itself (without progesterone)
  • Had trouble getting pregnant
  • Had fewer than five periods in a year before starting menopause
  • Taken tamoxifen
  • Family history of uterine, colon, or ovarian cancer

Late-Stage Cancer Diagnosis Incidence and Mortality