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Vaccination Equity for Prevention of Mpox

In the United States the JYNNEOS vaccine has FDA approval for the prevention of mpox and smallpox. It can be given either via:

  • Subcutaneous (under the skin)
  • Intradermal (in between layers of the skin)

Both are equally effective and require getting a shot (usually in the arm). Unvaccinated people have a 14 times higher risk of monkeypox disease than those who got vaccinated.

Note: People with darker skin especially Black , Latino, or Asian people, and people ages 20 - 30 are more likely to develop keloid scars as a reaction to skin injury.

If individuals have had keloid scarring in the past or have concern they will have keloid scarring, JYNNEOS can be administered:

  • Subcutaneously

If you have concerns, you may discuss this with your provider or vaccinator.