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Vaccination Equity for Prevention of Mpox

In the United States, the JYNNEOS vaccine has been approved by the FDA for the prevention of mpox and smallpox. It can be given either via:

  • Subcutaneous (under the skin)
  • Intradermal (in between layers of the skin)

Both are equally effective and require a shot (usually in the arm). Unvaccinated people have a 14 times higher risk of monkeypox disease than those who got vaccinated.

Note: People with darker skin, especially Black, Latino, or Asian people, and people ages 20 - 30 are more likely to develop keloid scars as a reaction to skin injury.

If individuals have had keloid scarring in the past or are concerned they will have keloid scarring, JYNNEOS can be administered subcutaneously.

If you have concerns, you may discuss this with your provider or vaccinator.