Clinical Lab Improvement Amendments (CLIA)


Welcome to the Illinois Clinical Laboratory Improvement Amendments (CLIA) Program. The program's mission is to ensure the highest quality of laboratory testing is performed in the state through the use of education and enforcement of state and federal CLIA regulations.


Under CLIA, a laboratory is defined as a facility that performs testing on materials derived from the human body for the purpose of providing information for the diagnosis, prevention, or treatment of any disease or impairment of, or the assessment of health of, human beings. These examinations also include procedures to determine, measure, or otherwise describe the presence or absence of various substances or organisms in the body. This program certifies, inspects and monitors clinical laboratories for compliance of state and federal CLIA regulations, and investigates complaints received to ensure clinical laboratory testing is accurate, effective and reliable. Feel free to contact the program for answers to technical and regulatory questions (see CONTACT US in the right-hand column).